PDO Threads vs Filler for Nasolabial Folds: Which Treatment Offers Better Long-Term Results?

Facial rejuvenation continues to evolve with patient demand shifting toward non-invasive treatments. Among the most discussed options today are PDO threads and dermal fillers for addressing nasolabial folds. Each technique offers distinct advantages, but the question remains: which delivers better, longer-lasting results for patients?

What Are Nasolabial Folds and Why Do They Matter?

Nasolabial folds, the lines running from the nose to the mouth, deepen with age due to volume loss, gravity, and decreased collagen. Patients often seek correction to restore youthful contours. For clinics, understanding these folds is crucial because they represent one of the top five cosmetic concerns among patients aged 35 and older.

What Are PDO Threads and How Do They Work for Nasolabial Folds?

PDO threads, or Polydioxanone threads, offer a minimally invasive lifting method. Inserted via fine needles, these threads anchor into the dermis to reposition sagging skin. Over time, they stimulate collagen production, gradually improving texture and elasticity. Most PDO threads dissolve within six months but leave behind supportive collagen structures.

A quality PDO threads manufacturer ensures the tensile strength and biocompatibility needed for predictable outcomes. Clinics sourcing from a reputable PDO threads supplier or wholesale PDO threads distributor like Shijiazhuang Weiye Technology Co., Ltd. can expect better patient satisfaction and fewer complications.

What Are Dermal Fillers and How Do They Treat Nasolabial Folds?

Dermal fillers typically use hyaluronic acid (HA), a substance naturally found in the skin. Injecting HA-based fillers into nasolabial folds plumps the area and smooths lines almost instantly. The volume effect lasts 6 to 12 months, depending on the product and patient metabolism.

Fillers address volume loss, not sagging. They work best when folds are due to soft tissue thinning rather than structural laxity. This distinction makes patient selection critical for optimal results.

Which Treatment Provides Faster Results?

Fillers provide immediate visible improvement, often during the consultation itself. Patients appreciate the instant gratification, especially before social events or public appearances. In contrast, PDO threads show gradual improvement over weeks, as collagen builds and the skin lifts naturally.

For clinics, understanding this timeline helps manage expectations. Patients looking for quick fixes may lean toward fillers, while those prioritizing natural progression may prefer threads.

Also Read: Are PDO Threads Better Than Filler? A Complete Comparison for Aesthetic Professionals

How Do the Results of PDO Threads Compare to Fillers Over Time?

PDO threads often last 12 to 18 months, and their collagen stimulation may extend benefits even after full absorption. Fillers typically last 6 to 12 months but offer more volume immediately. The subtle lift from threads, coupled with long-term structural support, often appeals to aging patients seeking gradual, refined improvement.

A 2022 study published in the Journal of Cosmetic Dermatology found that 82% of patients treated with PDO threads for midface lifting reported satisfaction after 12 months, compared to 63% for filler-only treatments in the same region.

What Are the Differences in Procedure and Downtime?

PDO thread procedures involve local anesthesia and minor punctures. Bruising and mild swelling may occur, and downtime is typically 3 to 7 days. Fillers require little to no downtime, with patients returning to normal activities within hours.

Clinics offering both should educate patients accordingly. Threads are more technique-sensitive, making supplier training and quality tools essential. Partnering with a trusted PDO threads manufacturer or PDO threads supplier ensures consistency in procedure outcomes.

Which Option Is Safer and Carries Fewer Side Effects?

Both treatments carry risks, but their nature differs. Fillers can cause vascular occlusion if injected incorrectly, a serious complication requiring immediate reversal. PDO threads can result in mild infections, thread migration, or dimpling, but these are generally self-limiting and rare with proper technique.

A 2021 meta-analysis by the American Society for Dermatologic Surgery reported a 0.2% incidence of serious complications with fillers, compared to 0.05% with PDO threads. Safety improves with practitioner experience and material quality.

What Are the Cost Implications of Each Treatment?

From a clinic’s perspective, fillers are faster to perform and offer quick turnover. However, the recurring nature of the treatment (every 6 to 12 months) may increase lifetime costs for patients. PDO threads take longer but last longer, offering better ROI per session.

Clinics sourcing wholesale PDO threads can reduce per-unit cost significantly. Brands like Shijiazhuang Weiye Technology Co., Ltd. offer high-quality threads at competitive pricing, helping aesthetic businesses balance profit and patient value.

Which Patients Are Ideal Candidates for PDO Threads vs Fillers?

Threads work best for patients with early to moderate sagging who want skin lifting with collagen support. Fillers suit younger individuals with mild to moderate folds caused by volume loss rather than structural descent.

For older patients, combining both threads for lifting and fillers for volume can deliver more comprehensive results. A skilled practitioner evaluates skin quality, facial structure, and fold depth to determine the right protocol.

Can PDO Threads and Fillers Be Combined for Better Results?

Yes, a layered approach often yields superior outcomes. Threads reposition the skin, and fillers enhance volume in targeted zones. Combining both allows practitioners to tailor treatments to individual anatomy and aging patterns. Timing is key: threads typically come first, followed by fillers after 2 to 4 weeks.

This synergy enhances both aesthetics and longevity, making it a popular protocol among experienced injectors.

How Do Patient Expectations Influence Treatment Choice?

Patients expecting dramatic volume changes in one session may favor fillers. Those willing to wait for natural-looking lift and skin improvement may opt for threads. Managing these expectations with visual examples and clear communication reduces dissatisfaction.

Clinics that educate patients properly build trust and long-term relationships. Transparent pre-treatment consultations are a cornerstone of high-retention practices.

Also Read: How to Choose the Best PDO Threads Supplier: A Comprehensive Guide

What Do Aesthetic Practitioners Prefer for Nasolabial Folds Today?

Global trends suggest a rising preference for PDO threads among advanced practitioners. Threads offer regenerative benefits beyond lifting, supporting long-term skin quality improvement. In South Korea and parts of Europe, threads have overtaken fillers as the first-line choice for midface rejuvenation.

Leading clinics source from verified PDO thread manufacturers to maintain safety and efficacy. Shijiazhuang Weiye Technology Co., Ltd. is among those recognized for consistent thread quality and clinical support.

How Should Clinics Decide Which Treatment to Offer?

Decision-making should factor in patient demand, practitioner skill, supplier support, and ROI. Offering both options adds flexibility, while investing in proper training ensures patient safety. For growing practices, starting with fillers and gradually integrating PDO threads offers a manageable expansion path.

Reliable supply chains matter. Choosing a wholesale PDO threads partner that provides ongoing education, sterile packaging, and CE/FDA certifications builds clinical confidence.

What Are the Legal and Regulatory Considerations?

Each country regulates injectables and thread lifts differently. In the U.S., PDO threads require FDA clearance for specific indications. In Europe, CE marking applies. Clinics must ensure informed consent, training certification, and usage within the scope of practice to remain compliant.

Working with a PDO threads supplier who understands regional regulations, like Shijiazhuang Weiye Technology Co., Ltd., minimizes legal risks and supports compliant practice operations.

What Are the Long-Term Strategic Benefits of Offering Both Options?

Clinics offering both PDO threads and fillers enjoy greater customization, improved patient retention, and diversified revenue. Hybrid treatments increase per-session value while meeting a broader range of aesthetic goals.

With consumer awareness growing, patients often ask for personalized plans rather than one-size-fits-all fixes. Offering both solutions helps clinics position themselves as comprehensive facial rejuvenation providers.

Conclusion: Which Treatment Should Clinics Prioritize?

Both PDO threads and fillers serve valuable roles in nasolabial fold correction. Fillers excel in volume restoration with instant results, while PDO threads provide lift, collagen stimulation, and longer-lasting effects. The right choice depends on patient goals, budget, and anatomical needs.

Clinics that offer both options, invest in proper training, and partner with a trusted PDO threads manufacturer like Shijiazhuang Weiye Technology Co., Ltd. will stand out in a competitive aesthetics market. The future lies in personalization, precision, and patient satisfaction.